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The Institute of Medicine offers a general guide of roughly 91 ounces per day for women and 125 ounces per day for men
These warnings are listed in the drugs prescribing information
Wegovy EPAR Public Assessment Report
What to know about retatrutide, updated July 2026
[1] The most frequently reported side effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, abdominal pain, and constipation
Some patients prefer injecting in the evening when they can rest if side effects occur, while others inject in the morning to avoid evening injection site reactions interfering with sleep
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