They're broader-acting compared to AOD-9604
Collapsible content What is the restore phase
Research from multiple sites and platforms contributes to the growing body of knowledge on these compounds and expands our understanding of cellular energy regulation, muscle physiology and metabolic adaptation mechanisms
When the PI3K/Akt signaling pathway is activated, NRF2 directly increases G6PD, 6PGD, TKT, and TALDO expression to enhance metabolic activities and promote cancer cell growth (58)
Activation of Nrf2 increases iron storage, reduces iron uptake by cells, and limits lipid ROS production (Hassannia et al., 2019
Should be used in conjunction with a program of reduced intake of dietary calories and increased physical activity