doi:10.1056/NEJMoa2410659
Oral semaglutide was then investigated in eight global Peptide InnOvatioN for the Early diabEtes tReatment (PIONEER) phase IIIa trials in over 8,000 patients, with similarly broad evaluation in different patient populations who were receiving a range of background medications ( Table 1 )
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GLP-1s, also known as GLP-1 receptor agonists (GLP-1RAs), stimulate the release of insulin, keeping blood sugar levels normal [3,5,9]