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In Parkinsons disease (PD), oxidative stress is closely associated with the degeneration of dopaminergic neurons in the substantia nigra

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Carnitine is a nitrogen-containing compound that is necessary for the transport of long-chain fatty acids into the mitochondria for oxidation

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Activated PKA promotes the PI3K/mTOR pathway in -cells, leading to the activation of the Hypoxia-Inducible Factor 1 (HIF-1)

Cinchonine (50 mg/kg or 100 mg/kg) was administered orally twice daily to the mice