attia glp 1 320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) - efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape Could GLP-1s impact aging and

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Though these are a normal part of human metabolism, they cause significant oxidative stress over time, damaging DNA inside cells and leading to premature aging

Very rarely, more serious reactions can occur, such as a severe allergic reaction

As oral GLP-1s are going to expand access to the drugs, gaining an understanding of these mechanisms is especially relevant, they added

Reduce inflammation and speed up recovery from injuries

ROS initiate autophagy by activating the AMPK pathway and inhibiting the mTOR signal