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Two of the three sequences are nearly identical and therefore were considered as the products of the same gene

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J Biol Chem 283(26):1836518376

Since 2016, Aspergillus fumigatus (associated with a mortality rate of 50%90%), Cryptococcus neoformans (20%70%), and Candida albicans (20%40%) have been recognized as the leading causes of life-threatening fungal infections (Vandeputte et al., 2012

It is administered as a once-weekly subcutaneous injection following a structured dose-escalation schedule, typically starting at 2 mg and increasing to 812 mg weekly in Phase 2 protocols