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B12 deficiency produces a recognizable cluster of symptoms: fatigue, weakness, neurological changes including tingling or numbness in the extremities, cognitive fog, and in more severe cases, megaloblastic anemia
Consider monitoring heart rate and blood pressure at baseline and regularly throughout treatment if these agents must be used together
Vitamin B12 or folate deficiency anaemia Complications
Low iron stores a thyroid that is technically in range but not functioning optimally
Individuals with MTHFR variants may rely more heavily on active B12 forms like methylcobalamin or adenosylcobalamin, depending on methylation response
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