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Prevent foam by avoiding any shaking motion and injecting water slowly down the vial wall

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Some GPs may incorrectly believe that only patients with a definite diagnosis of PA, those with a positive intrinsic factor antibody test, require treatment for life so seem to be using this as their treatment exclusion criteria

NNMT catalyzes a reaction where it takes methyl groups from the bodys universal methyl donor (SAM) and transfers them onto vitamin B3, producing what is essentially a metabolic dead end

Patients need to watch for signs of a B12 deficiency