Your BMI is 27 or higher and you have a weight-related medical condition, like sleep apnea, Type 2 diabetes, or heart disease
[1] Dose-escalation studies, such as a 12-week trial on gradual titration, revealed that beginning at lower doses (e.g., 4 mg) and slowly increasing to therapeutic levels significantly reduced the incidence of nausea, vomiting, and diarrhoea
We learned from that (about) very clear attributes the consumer was looking for
In addition to being a glucagon-like peptide 1 (GLP-1) receptor agonist, like semaglutide, tirzepatide also mimics glucose-dependent insulinotropic polypeptide (GIP), a hormone involved in blood glucose regulation and the storage of excess energy in fat cells
Editorial: selenium, human health and chronic disease
Most of the time, starting is the hardest part, and you'll manage more once you begin