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Notably, patients with obesity alone had higher discontinuation rates at 12 months (50.3%) compared to those with T2D alone (35.8%) and those with both conditions (34.2%)

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doi:10.1016/S0140-6736(23)01053-X PubMed: This trial evaluated retatrutide in 281 participants with type 2 diabetes, showing up to 16.94% weight loss and significant HbA1c reductions with favorable safety profile comparable to other GLP-1 based therapies