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A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]

Here we present the antioxidant GSH as a potential unexplored way for further investigation as intervention to counteract inflammaging, premature inflammaging, inflammatory diseases and long-COVID-19-syndrome, since GSH levels are correlated with tissue and organ damage, disease severity and progression, and disease outcome (294296, 298, 299)

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Under clinical supervision with proper selection and dosing, peptide therapy is generally well tolerated for appropriate candidates