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Tirzepatide (with Pyridoxine) : Tirzepatide is a dual agonist at GIP and GLP1 receptors, originally developed for type 2 diabetes, and is now widely used for significant, clinically meaningful weight loss and metabolic health improvements

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Mizuno M, Kuboki Y

Notably, it often causes severe functional impairment

The combined effects of multiple agents on gastric motility, glucose excretion, and immune modulation may cumulatively influence UTI risk