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Treatment selection should therefore take into consideration efficacy, adverse event profile, hypoglycaemia risk, weight control, presence of comorbidities and CV/CKD risk, as well as cost to patient [13,14,15, 24]

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Typical daily range: 100300 mcg of each peptide once daily (gradual titration)

Melanocyte stimulating hormone peptides inhibit TNF-alpha signaling in human dermal fibroblast cells