Incidence Rate Comparisons Preliminary Rates : Recent post-marketing surveillance data indicates that NAION reports occur at similar frequencies across the GLP-1 receptor agonist class, with an estimated incidence of 8.9 per 100,000 person-years for semaglutide compared to preliminary estimates of 9.7 per 100,000 person-years for tirzepatide
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This and other data indicate that NPY is also one of the most important hypothalamic-derived neuropeptides mediating the effects of leptin on overall energy homeostasis
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It also has expanding real-world data and emerging cardiovascular outcome results
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