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Furthermore, gene-editing therapies targeting Angiopoietin-like 3 (ANGPTL3) 399,400 and LDLR 401,402 have entered the preclinical stage, highlighting the broader potential of gene-editing-based lipid-lowering strategies, and long-acting therapies that provide stable and durable lipid-lowering effects could further reduce the risk of cardiovascular events

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For now, the drugs seem to have a really big impact on people who need them, helping them lose weight and feel better

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Adults with Obesity: BMI 30 History of Failed Weight Loss: People who have not achieved enough weight loss through diet and exercise alone