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Key Takeaways: GLP-1s have transformed diabetes care, generating $23 billion in sales in 2022

population has filled a GLP-1 prescription, representing roughly 9-15 million individuals across diabetes, weight loss, and cardiovascular indication categories

This use is not recommended and carries several safety risks , particularly changes in pigment lesions that may mask melanoma

According to the literature, blood ammonia levels are not highly correlated with blood L-carnitine levels [21]

GI tolerability exceeding current incretin therapies, particularly vomiting, which is a common reason for therapy discontinuance