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However, the body weight of 5A-1MQ-treated obese mice (WD/LD-T group), which was indistinguishable from the other DIO groups at study start, was indistinguishable from the lean control (LD/LD-V) group at study completion (results with FDR correction
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NNMT regulates pathways that can affect NAD+ availability and overall metabolic efficiency
One proposed benefit is the partial bypass of the gastrointestinal absorption pathway , which can be compromised in various clinical scenarios
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