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study in Gastroenterology remains the foundational paper supporting KPV as one of the leading peptides for gut health via its oral delivery mechanism, demonstrating PepT1-mediated transport in Caco-2 cell models and murine colitis models with measurable reductions in colonic inflammation

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This suggested that parkin-induced ECSIT ubiquitination is upstream of LC3BII recruitment for the initiation of mitophagy (Carneiro et al., 2018), It is not clear whether ECSIT participates in receptor-mediated mitophagy like other mitochondrial outer membrane proteins such as FUNDC1, NIX, and BNIP3

Tacchetti, C

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If symptoms persist, seeking medical attention is recommended