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As a novel antidiabetic agent, glucagon-like peptide-1 (GLP-1) exerts a renoprotective effect in DKD rats via activation of autophagy through AMPK-mTOR pathway (155)
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It activates both GIP and GLP-1 receptors, which decreases appetite, slows gastric emptying, and improves the hormonal environment around glucose metabolism
705-165-147, RRID: AB_2307351) and Alexa-Fluor 488 donkey anti-goat (1:250
GLP-1R agonists may improve the function of the gut-brain axis and stability of the gut microbiota Many recent reports also emphasize the role of the gut-brain axis and stability of the gut microbiota in the development of mood disorders, including depression