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109 Moreover, NAD + -consuming enzymes, such as SIRT3, can also manipulate the cellular redox status via regulating the activity of enzymes for ROS generation and antioxidant factors for ROS eradication
The "LR3" modification (a substitution at position 3 and an arginine extension) reduces IGF-1 LR3's affinity for IGF-binding proteins (IGFBPs)
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