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using liraglutide 3 mg/day compared with placebo, despite the lack of changes in total testosterone levels, confirmed the increase in SHBG levels, with a consequent reduction in free Androgen Index (FAI), and also a restoration in menstrual cyclicity [62]

In fact, the expression of GLP-1R mRNA in the pituitary was lower than in the hypothalamus and even declined during the estrous cycle [35]

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation