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GLP-1 receptor agonists are a class of medicines used mainly for type 2 diabetes and, in some cases, obesity or overweight with weight-related health problems

Ozempic is not an insulin and should therefore not be used as a substitute for insulin

Research also shows that combining Ozempic with metformin can lead to even greater improvements in blood sugar control, especially for those who are overweight or managing other risk factors

Describing herself as largely 'the lab rat' when she joined the diabetes team, Knudsen remembers she spent 'the first year in a cold room with three technicians to screen hundreds of thousands of compounds to see if they could wedge into the GLP-1 receptor and other targets of interest just snugly enough to stimulate insulin secretion.' To help speed up the screening process, Knudsen devised a method to test 96 candidates in one go instead of just one

Together with lifestyle changes like a reduced-calorie diet and increased physical activity, Mounjaro helps control blood sugar levels

C., Li, L