PEPTIDE SCIENCES COUPON/DISCOUNT To welcome researchers to our new platform, Peptide Sciences offers exclusive savings opportunities
3 Extended Administration Pharmacokinetics in DIO Mice Neelakantan et al., Biochemical Pharmacology (2024) This study reported a 28-day once-daily administration protocol of 5-Amino-1MQ in diet-induced obese mice, characterizing plasma pharmacokinetics, tissue distribution, and effects on body composition, fatty liver pathology, and circulating biomarkers
Always consult a qualified healthcare professional before starting or modifying any treatment, including the use of investigational peptides such as AOD-9604
Oral bioavailability has not been clearly measured in humans
In mouse models of highfat dietinduced obesity, it treatment significantly reduced mRNA and protein expression of TNF, IL6, and other inflammatory factors in adipose tissue and decreased macrophage infiltration - a hallmark of adipose inflammation
NNMT is an enzyme that converts nicotinamide to N-methylnicotinamide, consuming methyl groups and potentially reducing NAD+ availability