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One study found that even short-term sleep deprivation led to significant reductions in glutathione in certain tissues, due to heightened oxidative load

Mutation Research , 256(2-6), 221-231

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Hives are raised red or skin-colored welts or rashes that typically flare up suddenly and have a habit of changing shape or moving from one area of the body to another

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This makes them a popular ingredient in anti-aging products