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The nanoparticles were found to preferentially accumulate in plaque-resident cells, including VSMC-like cells, and targeted cells exhibited a lower inflammatory status, as shown by decreased Tnf and Icam1 expression with a concomitant increase in Arg1 , a marker of alternative macrophage activation

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A trial published in the New England Journal of Medicine enrolled adults with a BMI (body mass index) of 30 or higher, or between 27 and 30 with weight-related conditions (e.g

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