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Patients usually come into our Miami clinic with a specific objective, not a generic interest in growth hormone
10.1111/bdi.12652 110 DingX.LiQ.LiP.ChenX.XiangL.BiL.et al
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BMPs regulate NSC differentiation into astrocytes by acting through the phosphorylation of Smad proteins 1, 5, and 8, which combine with Smad4 in order to form a complex that translocates to the nucleus and regulates gene transcription (Itoh et al., 2000
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In contrast, male lifespan tended to be reduced by early-life IGF-1 deficiency, which is in agreement with a prior study in LID mice 41
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