Off periods of 2-4 weeks between cycles are common
and participates in the action of serotonin, a neurotransmitter known to control mood and appetite
PubMed Philp, D., Badamchian, M., Scheremeta, B., Nguyen, M., Goldstein, A.L., & Kleinman, H.K
Preclinical work, predominantly from Sikiric and colleagues, has examined its activity in gastrointestinal ulcer models, tendon and ligament repair models, and endothelial/VEGF (vascular endothelial growth factor)-linked angiogenesis pathways
Despite its announcement to the stock exchange in 2007 that trials showed at 24 weeks participants lost one kilogram at best, only last month Metabolic told its patent holders that it was going ahead with attempting to license the product in the US for use in sports drinks and dietary supplements
Benefits will vary based on ones' lifestyle therefore the best guage for frequency will be how you feel.