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Understanding When Elevated B12 Requires Investigation In individuals who are not supplementing, elevated B12 levels can sometimes point to underlying health issues such as liver disease, certain blood disorders, or kidney disease
These numbers were based on 95% confidence intervals of MMA levels among apparently healthy people with normal serum B12 and kidney function
Still, there are cases where B12 injections are the better bet
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However, a study found that taking 1,000 mcg of B12 by mouth or injecting the vitamin achieved similar results in treating the deficiencies
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Thain A, Hart K, Ahmadi KR European journal of clinical nutrition 2025
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