Journal of Diabetes Investigation
Journal of Endocrinology, 188 (2), 135153
Semaglutide is the active ingredient in the brand-name drugs Ozempic, Wegovy, and Rybelsus , all of which are also made by Novo Nordisk
Neurology referral should be considered for atypical presentations (asymmetry, motor involvement, rapid progression, prominent autonomic features) or treatment-refractory cases
It has become a life-changing option for overweight or obese people who are committed to losing weight and do not have any serious health problems
But patients are: Suffering from autoimmune disease NOW Struggling with PCOS NOW Fighting addiction NOW Accumulating visceral fat in midlife NOW Developing cardiovascular disease and cognitive decline NOW Were offering them: A biologically plausible intervention With an excellent safety profile at low doses Under careful monitoring With full disclosure of evidence limitations The prosecution is offering them: A decade of continued suffering While we wait for studies that pharmaceutical companies wont fund Because theres no profit in proving generic semaglutide works at 0.15 or 0.25 mg for off-label indications