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No clinical safety or efficacy issues were identified

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If more than five days have passed, the missed dose should be skipped, and the next dose should be administered on the regularly scheduled day

This is usually followed by a break of equal or longer length to give receptors a chance to reset

High infectivity yield was obtained at residence times greater than 3 min for GSH Sepharose 4 FF and Pierce Glutathione columns, while lower yields were observed across all residence times for GSH Sepharose 4B

From a mechanistic perspective, this could be interpreted as an increased responsiveness to endogenous repair signals