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Oral doses used in animal studies are typically three to ten times higher than equivalent injectable doses to produce comparable systemic effects suggesting oral bioavailability in the range of 1030% relative to parenteral delivery.3 That does not mean oral BPC-157 is ineffective

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Georgiadis JR, Reinders AA, Van der Graaf FH, Paans AM, Kortekaas R

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8 Thyroid hormones play a role in brain chemistry, affecting serotonin and other neurotransmitters involved in mood

This ratio becomes problematic for several reasons