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Altered mental status : Significant confusion, disorientation, or difficulty staying awake Contact your healthcare provider promptly (within 2-4 hours) for: Moderate nausea and vomiting that interferes with fluid intake Blood glucose readings consistently below 70 mg/dL despite treatment Persistent diarrhea or gastrointestinal symptoms lasting beyond 24 hours Inability to eat or drink for more than 12 hours Symptoms that are worsening rather than improving Uncertainty about how to manage your situation Special populations requiring lower threshold for medical evaluation: Elderly patients (over 65 years) Individuals with kidney disease or impaired renal function Patients taking insulin or sulfonylureas concurrently Those with history of pancreatitis Pregnant or breastfeeding women Patients with cardiovascular disease When contacting medical services, provide specific information including the dose taken, timing of injections, current symptoms, blood glucose readings if available, and your complete medication list