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This can impair astrocyte regulation of the tripartite synapse, BBB, and neuronal metabolism

The receptor mechanism is identical

Our full MOTS-c research guide goes deeper on dosing figures and the metabolic literature

Figure 4: Eating too much protein from animal products and nuts can stop the body from properly recycling homocysteine (Hcy), raising Hcy levels

The NHS guidance on vitamin B12 deficiency treatment recommends a loading course of injections first, followed by regular maintenance doses