It protects DNA, proteins, and lipids from oxidative damage, helping sustain optimal cell function and long-term tissue health in both physiological and experimental research settings
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Glutathione reductase plays a vital role in cellular defense against oxidative stress by maintaining high levels of reduced glutathione in the cytosol, which is essential for detoxifying reactive oxygen species and protecting cellular components from oxidative damage
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Cysteine contains sulfur and gives glutathione its sulfuric aroma
Furthermore, in the presence of S-nitrosylated PDI, the formation of mutant SOD1 aggregates increases in vitro (Jeon et al., 2014)