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Unfortunately, NAD+ levels decline with age, stress, poor diet, and metabolic dysfunction

It was also noted that postmenopausal women exhibited more pronounced declines than premenopausal women or men

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Carvajal-Flores FN, Daz A, Flores-Gmez GD, de la Cruz F, Flores G (2020) Phenylbutyrate ameliorates prefrontal cortex, hippocampus, and nucleus accumbens neural atrophy as well as synaptophysin and GFAP stress in aging mice

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