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PMCID: PMC4969472

A study examining plasma samples from 50 migraine patients and 30 healthy volunteers found that plasma levels of 8-hydroxy-2-deoxyguanosine were significantly higher in migraine patients compared to controls, indicating a connection between migraine and oxidative stress-related DNA damage (Table 1)

Next, to assess the identified metabolites and clinical phenotypes in further detail, we analyzed their association with visual field grades, because visual field loss is one of the most important criteria for intervention