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Nrf2-dependent antioxidant response mediated the protective effect of tanshinone IIA on doxorubicin-induced cardiotoxicity

Bariatric surgery should be considered in patients with severe obesity, advanced obesity complications, inadequate response to medication, or when durable remission of obesity-related disease is a major treatment goal

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Reports of severe adverse events include allergic reactions ranging from mild rashes to anaphylactic shock, kidney dysfunction particularly with high doses or prolonged use, liver toxicity in susceptible individuals, and thyroid dysfunction affecting hormone regulation

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