J Mater Chem C 2:595613
As noted by the authors, GSH can also directly participate in the formation of disulfide bonds necessary for antibody production and NADPH is necessary for continual lipid rearrangement required for Ig secretion 134,135
Moreover, it is required for the transport and metabolism of fats and cholesterol, which is important for the healthy support of the endocrine, cardiovascular, and hepatic systems
Although the evidence for excess folic acid exacerbating vitamin B12 deficiency is weak, it is prudent to increase vigilance for identifying B12 deficiency in at-risk individuals, including older adults and others with low B12 intake or conditions that are associated with B12 malabsorption, who also ingest excessive folic acid or are prescribed folic acid in high doses (169)
1948: Folkers and Todds isolation confirmed B12 as the anti-pernicious anemia factor, with a molecular weight of 1,355 Da and a red color due to cobalt
Not catastrophically wrong, but wrong enough to leave results on the table