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Overall, the weight of evidence to date does not support a role for FGF21 in mediating bone remodeling in adult humans

Sedentary weight loss from GLP-1 alone sometimes includes modest muscle loss, which resistance or functional movement can mitigate

Lilly noted, however, that dropouts were highly correlated with baseline BMI and included discontinuations for perceived excessive weight loss. The company also pointed out that participants with a higher BMI were less likely to drop out

To be somewhat blunt about it: Rasa has notes of a milder Ricola cough drop

GLP-1 receptors are present in brain regions involved in rewards and craving

They can protect lean body mass and micronutrient status during weight loss (which is often rapid with GLP-1s)