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As hormone-mimicking therapies, GLP-1 and GLP-1/GIP act on natural pathways that help regulate appetite, insulin signaling, and inflammation

Constipation tends to last longer than the other effects because of its more chronic nature, while nausea clusters around the adjustment phases

The NHS should introduce a stepped care approach through online support available to large numbers of people at low cost, online or in-person group support or more intensive 1:1 support. Jason Halford, at the European Association for the Study of Obesity, said: We need to ensure patients have the support to make the changes in their behaviour they need to sustain the benefits of treatment

When you receive your prescription, you will get a box containing four single-use pens, which will last for about one month (28 days)

It is best to inject on the same day and at the same time each week to maintain stable medication levels and consistent results