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Lamb, K

doi: 10.3390/cancers14071814 245 KellyASHalePM

A single dose of rituximab does not deplete B cells in secondary lymphoid organs but alters phenotype and function

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The Math The formula for any vial size and any amount of water: Concentration = Peptide Amount (mcg) / Water Added (mL) For injection volume: Units to inject = Desired Dose (mcg) / Concentration (mcg/mL) x 100 Example: 5,000mcg vial + 2mL water = 2,500mcg/mL

This was essentially exenatide embedded in biodegradable microspheres, allowing it to slowly release over 7 days