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GLP-1 receptor agonists and risk for cirrhosis and related complications in patients with metabolic dysfunction-associated steatotic liver disease
It has been demonstrated that GSTP1, a member of the GST family, protects cells from ferroptosis by catalyzing the conjugation of GSH to 4-hydroxynonenal (4-HNE) through its selenium-independent GSH peroxidase activity (Zhang, et al
This means that only a fraction of the ingested glutathione may reach the bloodstream and exert its beneficial effects
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There is also other early research that shows that GLP-1 can be an effective treatment for drug or alcohol addiction, so we will likely see the medication be used beyond diabetes and obesity in the future.
Loncharich, R
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