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Their main use is as an add-on to metformin in patients who are insufficiently controlled on metformin alone, and an important indication is also in combination with insulin therapy.
PubMed PMID 30915550 review of BPC-157 in musculoskeletal soft-tissue research, emphasizing that most evidence comes from small-animal models
Do not use GLP-1s if you: Have a personal or family history of certain types of thyroid cancer (e.g., medullary thyroid carcinoma) or multiple endocrine neoplasia type 2 Have had pancreatitis or gallbladder disease unless cleared by your doctor Are pregnant, planning to become pregnant, or breastfeeding Have severe gastrointestinal disease (consult your healthcare provider) Common side effects may include: Nausea, especially during the first few weeks Constipation or diarrhea Fatigue or low energy Mild stomach cramping Temporary decrease in appetite To reduce side effects, your provider will typically start with a low dose and increase gradually
It is possible to buy a private vitamin B12 self-test, which will either be in the form of bloods being taken by a professional or as finger-prick blood sample to do yourself via post
Retatrutide (LY3437943) is an investigational triple GLP-1, GIP, and glucagon receptor agonist developed by Eli Lilly, with Phase 2 clinical data published in 2023 showing dose-dependent body weight reductions and HbA1c improvements
Combined, the ingredients are purported to promote skin quality, collagen production, wound healing, and recovery
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