observed that the gut microbiota of diet-induced obese (DIO) mice treated with liraglutide for four weeks displayed a similar phylogenetic composition in comparison to the start of the treatment, but was characterized by a significant decrease in microbial phenotypes associated with obesity (e.g., Firmicutes Lachnospiraceae and Clostridiales ), alongside an increase in Proteobacteria (e.g., Burkholderiales bacterium YL45 ) and Akkermansia muciniphila a species largely associated with high-fibre diets and mucosal barrier health (11, 6971)
Mode of Failure: Physical Stability For low water activity (0.20-0.40 aw) products such as snacks, dry pet food, and food powders, chemical reactions and microbial contamination are not the most likely modes of failure
(PubMed) Pesce V, Fracasso F, Cassano P, Lezza AM, Cantatore P, Gadaleta MN
& Bates, D
Seventy percent
Methylglyoxal impairs energy production and the anti-oxidative protective effects, thereby contributing to the enhanced PS exposure of circulating erythrocytes and ultimately resulting in anemia and microcirculatory disequilibrium [321]