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In 1949, Australian physician John Cade used high doses of the mineral to treat mania. By the 1970s, pharmaceutical lithium had been approved by the FDA for acute mania and recurrent mania, and it became the standard treatment for manic depression
Eur Heart J (2017) 38:294856
More targeted research examining bone turnover markers and bone mineral density (BMD) measurements has shown inconsistent results
doi:10.1017/cbo9780511711930
K.VeluC
Some human topical GHK-Cu research has used study periods around 12 weeks
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