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For instance, the FXR agonist obeticholic acid (OCA) has been demonstrated to attenuate systemic inflammation by inhibiting the NF-B signaling pathway, while TGR5 activation similarly suppresses macrophage inflammatory responses 164,165,166

10.7759/cureus.14029 Cureus 120 WangY.WangK.LiangJ.YangH.DangN.YangX.et al (2015)

Plasma and urinary carnitine and acylcarnitines in chronic fatigue syndrome