Unfortunately, studies show that folks tend to gain some (or all) of the lost weight back after they come off semaglutide
The packaging may introduce contamination during filling
One side effect some people report is feeling cold
When to contact your GP: Persistent severe nausea or vomiting that prevents adequate fluid intake Signs of dehydration (dizziness, dark urine, reduced urination) Severe abdominal pain that could indicate pancreatitis Symptoms of very low blood sugar (confusion, sweating, trembling) if taking other diabetes medications Blood pressure readings consistently below 90/60 mmHg or above your target range Blood pressure readings of 180/120 mmHg or higher, especially with symptoms such as severe headache, chest pain, or vision problems (seek same-day medical assessment) Any new or concerning symptoms Your healthcare team may adjust your blood pressure medications if your readings improve significantly
One thing these drugs do is reduce the size of fat cells
Effect estimates remained robust when restricting to patients with available hemoglobin A1c and including it in the propensity score (Supplementary Table 23)