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While some receptor adaptation does occur (explaining why gastric emptying effects attenuate over time even as doses increase), the central appetite-suppressing effects appear to be maintained through mechanisms that do not rely solely on gastric motility

Increased heart rate a dose-dependent rise of about 5 to 10 beats per minutewas also seen, peaking around week 24 and declining afterward

Diabetes is present if HbA1c is 6.5% or more

and Rev

4 Discussion Antioxidant enzymes represent the first line of defence which has an important role to restrain the damage done by reactive oxygen molecules (ROS) of parasite origin [17], whereas the survival of parasite may rely on its ability to maintain the necessary balance between oxidation and antioxidation [38]

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