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Although findings from clinical studies are promising, there are concerns that long-term exposure of GLP-1 RAs at supratherapeutic or maximum approved maintenance doses may impair muscle cell differentiation and potentially contribute to the development of sarcopenia, despite their potential to improve muscle metabolism and quality [83, 88]

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Inflamm Bowel Dis (2019) 25:118795

Under federal law, when an FDA-approved drug is in shortage, compounding pharmacies may produce copies to help fill the gap