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Serious side effects remain the same as with other Wegovy doses, including potential risks of pancreatitis, gallbladder problems, kidney problems, and diabetic retinopathy in patients with diabetes

And once you stop, it takes roughly 5 half-lives, or about 35 days, for the medication to clear your system completely

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The landscape of weight loss medication has been revolutionized by GLP-1 and dual GIP/GLP-1 receptor agonists

In the obese trial cohort, 1 mg moved 24-hour ambulatory heart rate by +0.7 bpm at week 24 the peak of the heart-rate curve, and below the placebo arms +0.8. In a healthy lean Phase 1 group, the same dose raised heart rate by about 10 bpm, with a peak near 15 to 20 bpm around days 4 to 6. Lean, younger participants had more reactive heart-rate control than the sedentary, obese, and metabolically stressed trial population